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[232] [198] In addition to presynaptic actions that regulate DAT, TAAR1 activation exerts a somatodendritic inhibitory influence on midbrain dopamine neurons by reducing their firing rate via G protein-coupled inwardly-rectifying potassium channels, an effect that is expected to reduce action potential-dependent (vesicular) dopamine release into the synaptic cleft

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As you smoke this type of cigarette, expect to inhale more air

Leaded bronze components and degrading heating coils were identified as major sources of contamination

While we are encouraged by FDAs recent actions to curb unlawful marketing of flavored e-cigarettes, we all must work with even greater urgency to protect our nations youth from all flavored e-cigarettes, including disposables. What more can be done E-cigarette products, related policies, and use patterns change rapidly